UNIVERSITY OF WISCONSIN SYSTEM

GROUND SQUIRREL PURCHASE

FY 20 EXPIRING LINES

DR DAVIS RESEARCH INVESTIGATING THE ROLES OF THE NOVEL DIABETES GENE, TCF19 THROUGH THE USE OF KNOCKOUT MICE THAT LACK EXPRESSION OF TCF19 USE OF NORMAL MOUSE PANCREATIC ISLET TISSUE TO UNDERSTAND HOW TCF19 IMPACTS PANCREATIC ISLET SURVIVAL AGROWTH

INCREMENTAL FUNDING ACTION.

OPTION YEAR MODIFICATION

DR SAFDAR FLOW CYTOMETRY FOR GULF WAR ILLNESS RESEARCH WITH AFFILIATE UW MADISON

DR SAFDAR FLOW CYTOMETRY FOR GULF WAR ILLNESS RESEARCH WITH AFFILIATE UW MADISON

KIMPLE AND THE RESEARCH DEPARTMENT AT MADISON VA REQUIRES TESTING THE ROLES OF MOLECULAR MECHANISMS

DR ALBERTINI RESEARCH CANINE MELONOMA

DR DAVIS RESEARCH INVESTIGATING THE ROLES OF THE NOVEL DIABETES GENE, TCF19 THROUGH THE USE OF KNOCKOUT MICE THAT LACK EXPRESSION OF TCF19 USE OF NORMAL MOUSE PANCREATIC ISLET TISSUE TO UNDERSTAND HOW TCF19 IMPACTS PANCREATIC ISLET SURVIVAL AGROWTH

KIMPLE AND THE RESEARCH DEPARTMENT AT MADISON VA REQUIRES TESTING THE ROLES OF MOLECULAR MECHANISMS

FY 19 EXPIRING LINES

THE VA MERIT AWARD TO DR. CATHERINE GALLAGHER REQUIRES STATE OF THE ART MRI IMAGING OF THE BRAIN USING RESEARCH-SPECIFIC SEQUENCES AT A RESEARCH-DEDICATED FACILITY. THE UNIVERSITY OF WISCONSIN HAS RESEARCH MRI FACILITIES CAPABLE OF PERFORMING THIS SPECIALIZED IMAGING FOR HUMAN RESEARCH STUDIES, AS WELL AS SCAN OVERREADS REQUIRED BY THE INSTITUTIONAL REVIEW BOARD. THIS FACILITY WAS USED TO COMPLETE WORK FOR DR. GALLAGHER'S PREVIOUS MERIT AWARD, LONGITUDINAL MRI BIOMARKERS IN PARKINSON'S DISEASE, OF WHICH THE CURRENT CONTRACT IS A CONTINUATION.

THE ANIMAL RESEARCH FACILITY (ARF) OF THE MADISON VA HOSPITAL IS AN AAALAC (ASSOCIATION FOR ASSESSMENT AND ACCREDITATION OF LABORATORY ANIMAL CARE) ACCREDITED FACILITY THAT CURRENTLY HOUSES OVER 2,500 MICE AND RATS FOR USE IN RESEARCH. TO ACHIEVE AND MAINTAIN THIS ACCREDITATION, THE VA ARF IS REQUIRED TO HAVE AN ONGOING HEALTH SURVEILLANCE PROGRAM IN PLACE TO MAINTAIN THE HEALTH OF ANIMALS, TO PREVENT DISEASE OUTBREAK, AND TO MAINTAIN THE INTEGRITY OF THE RESEARCH. RELATED TO ANIMAL TESTING REQUIREMENTS, THERE IS ALSO A REQUIREMENT TO ROUTINELY TEST THE SANITATION OF ANIMAL HOUSING EQUIPMENT TO ENSURE PREVENTION OF DISEASE TRANSMISSION BOTH TO OTHER ANIMALS AND TO PEOPLE.

THE ANIMAL RESEARCH FACILITY (ARF) OF THE MADISON VA HOSPITAL IS AN AAALAC (ASSOCIATION FOR ASSESSMENT AND ACCREDITATION OF LABORATORY ANIMAL CARE) ACCREDITED FACILITY THAT CURRENTLY HOUSES OVER 2,500 MICE AND RATS FOR USE IN RESEARCH. TO ACHIEVE AND MAINTAIN THIS ACCREDITATION, THE VA ARF IS REQUIRED TO HAVE AN ONGOING HEALTH SURVEILLANCE PROGRAM IN PLACE TO MAINTAIN THE HEALTH OF ANIMALS, TO PREVENT DISEASE OUTBREAK, AND TO MAINTAIN THE INTEGRITY OF THE RESEARCH. RELATED TO ANIMAL TESTING REQUIREMENTS, THERE IS ALSO A REQUIREMENT TO ROUTINELY TEST THE SANITATION OF ANIMAL HOUSING EQUIPMENT TO ENSURE PREVENTION OF DISEASE TRANSMISSION BOTH TO OTHER ANIMALS AND TO PEOPLE.

DR ALBERTINI RESEARCH CANINE MELONOMA

DR DAVIS RESEARCH INVESTIGATING THE ROLES OF THE NOVEL DIABETES GENE, TCF19 THROUGH THE USE OF KNOCKOUT MICE THAT LACK EXPRESSION OF TCF19 USE OF NORMAL MOUSE PANCREATIC ISLET TISSUE TO UNDERSTAND HOW TCF19 IMPACTS PANCREATIC ISLET SURVIVAL AGROWTH

DR ALBERTINI RESEARCH CANINE MELONOMA

DR PUGLIELLI RESEARCH W/ UW MADISON - AFFILIATE SOLE SOURCE

RESEARCH STRIKER?S VA MERIT AWARD IS TESTING NOVEL SMALL MOLECULES FOR ANTIBACTERIAL PROPERTIES. THE UW MEDICINAL CHEMISTRY CENTER WILL PROVIDE DESIGN, SYNTHESIS, PURIFICATION, AND STRUCTURAL ANALYSIS OF NOVEL SMALL MOLECULE KINASE INHIBITORS, AND DELIVER THESE MOLECULES FOR TESTING IN 2 MG QUANTITIES TO BE PACKAGED IN SMALL VIALS FOR DELIVERY TO DR. STRIKER?S LAB.

LIVE ANIMALS

FY 18 EXPIRING LINES

THE VA MERIT AWARD TO DR. CATHERINE GALLAGHER REQUIRES STATE OF THE ART MRI IMAGING OF THE BRAIN USING RESEARCH-SPECIFIC SEQUENCES AT A RESEARCH-DEDICATED FACILITY. THE UNIVERSITY OF WISCONSIN HAS RESEARCH MRI FACILITIES CAPABLE OF PERFORMING THIS SPECIALIZED IMAGING FOR HUMAN RESEARCH STUDIES, AS WELL AS SCAN OVERREADS REQUIRED BY THE INSTITUTIONAL REVIEW BOARD. THIS FACILITY WAS USED TO COMPLETE WORK FOR DR. GALLAGHER'S PREVIOUS MERIT AWARD, LONGITUDINAL MRI BIOMARKERS IN PARKINSON'S DISEASE, OF WHICH THE CURRENT CONTRACT IS A CONTINUATION.

DR ALBERTINI RESEARCH CANINE MELONOMA

DR PUGLIELLI RESEARCH W/ UW MADISON - AFFILIATE SOLE SOURCE

FY 18 EXPIRING LINES

DR DAVIS RESEARCH INVESTIGATING THE ROLES OF THE NOVEL DIABETES GENE, TCF19 THROUGH THE USE OF KNOCKOUT MICE THAT LACK EXPRESSION OF TCF19 USE OF NORMAL MOUSE PANCREATIC ISLET TISSUE TO UNDERSTAND HOW TCF19 IMPACTS PANCREATIC ISLET SURVIVAL AGROWTH

THE ANIMAL RESEARCH FACILITY (ARF) OF THE MADISON VA HOSPITAL IS AN AAALAC (ASSOCIATION FOR ASSESSMENT AND ACCREDITATION OF LABORATORY ANIMAL CARE) ACCREDITED FACILITY THAT CURRENTLY HOUSES OVER 2,500 MICE AND RATS FOR USE IN RESEARCH. TO ACHIEVE AND MAINTAIN THIS ACCREDITATION, THE VA ARF IS REQUIRED TO HAVE AN ONGOING HEALTH SURVEILLANCE PROGRAM IN PLACE TO MAINTAIN THE HEALTH OF ANIMALS, TO PREVENT DISEASE OUTBREAK, AND TO MAINTAIN THE INTEGRITY OF THE RESEARCH. RELATED TO ANIMAL TESTING REQUIREMENTS, THERE IS ALSO A REQUIREMENT TO ROUTINELY TEST THE SANITATION OF ANIMAL HOUSING EQUIPMENT TO ENSURE PREVENTION OF DISEASE TRANSMISSION BOTH TO OTHER ANIMALS AND TO PEOPLE.

DR ALBERTINI RESEARCH CANINE MELONOMA

DR PUGLIELLI RESEARCH W/ UW MADISON - AFFILIATE SOLE SOURCE

DR KIMPLE AND THE RESEARCH DEPARTMENT AT MADISON VA REQUIRES TESTING THE ROLES OF MOLECULAR MECHANISMS BEHIND EP3 GAZ SIGNALING IN GLUCOLIPOTOXIC CELL COMPENSATION AND THE PROGRESSION TO T2D IN THE PREVENTION AND TREATMENT OF TYPE 2 DIABETES.

OPTION YEAR 3- ANNUAL PROVISION OF BREEDING AND COLONY MAINTENANCE FOR 100 LIVE ICTIDOMYS TRIDECEMLINEATUS (GROUND SQUIRRELS)